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Adverse Drug Events cause up to 3.5 billion in excess medical costs every year
US Institute of Medicine
At least 1.5 million preventable ADEs occur each year; these costly and sometimes fatal incidents include cases of drug mix-ups and unintentional overdoses
The National Academies Press
Nearly 30% of adults in the U.S. take 5+ medications
CDC
4.5 million Americans visit their doctors or the emergency room due to ADRs
FDA
Common Diseases with Drug to Drug Interactions that our PGx Test Includes
Prescribe with Precision
Precision Health Solutions is an expert in personalized medicine to help patients on their path to better health. Our pharmacogenomics (PGx) testing program improves outcomes through precise medication management based on a patients unique DNA.
Once-in-a-lifetime DNA Test
Reduce Polypharmacy
Increased Therapeutic Success
Reduce Adverse Drug Reactions (ADRs)
Genetically Tailored Dosage Insights for Current Medication Regimens
Actionable Medication Treatment Plan from Certified PGx Pharmacist
John has been taking Zoloft for his major depression for about 2 months. At his most recent visit with his psychiatrist, John said he is still not feeling better and is having side effects (dizziness, upset stomach, and anxious feelings). John has already tried several medications for his major depression without seeing a significant improvement. So, he and his psychiatrist decided to look deeper into what's causing these antidepressants to not be effective. A PGx test indicated that John is not able to eliminate Zoloft from his body which is what caused his poor experience. It also showed why his previous medications didn’t work properly and that helped his psychiatrist select a more appropriate medication that would have a higher likelihood of success in treating his condition.
Karen is thinking about taking a medication to help her to stop smoking. Her provider discussed placing her on Wellbutrin. Karen was nervous about taking this medication and wanted some information about how she may respond. Karen’s provider had a pharmacogenomics test run for her and it was discovered that Karen would not have the best results while taking Wellbutrin. This helped Karen’s provider from prescribing the wrong medication for Karen from the start instead of her experiencing unwanted side effects.
Gerald just began taking Zocor to help manage his high cholesterol. Within the first week of taking this medication, he started to experience intense muscle pain and weakness. It is possible that Gerald’s genetics are playing a role in how he removes this medication from his body. The build-up of Zocor in Gerald’s system could be linked to his genetics.
Mary has been taking Tramadol to help manage her osteoarthritis pain and complains that this medication does not manage her pain properly. This could be related to Mary’s unique genetic profile where she cannot properly activate Tramadol, which prevents this medication from providing proper pain control.
PGx Case Study
Data is based on 189 patients that were tested for pharmacogenomics (PGx) by Precision Health Solutions.
Drug Metabolism
Drug metabolism refers to how quickly one's body processes certain medicines. This can affect whether a medication will work or whether the drug will cause adverse effects.
Poor Metabolizer
A person who is a “Poor Metabolizer” for a medicine will process that medicine very slowly. The medicine might not work if it is processed slowly, or it could put them at risk for side-effects.
Intermediate Metabolizer
A person who is an “Intermediate Metabolizer” for a medicine will process that drug slowly, but not as slowly as a poor metabolizer. This means that the normal dosage of certain medicines may not work for them, or may cause side-effects.
Extensive Metabolizer
A person who is an “Extensive (Normal) Metabolizer” for a medicine usually benefits from the normal dosage of the medicine. This means the metabolizer status does not put them at increased risk for side-effects.
Rapid Metabolizer
A person who is a “Rapid Metabolizer” for a medicine can process the medicine very quickly. A medicine might not work if it is processed very quickly, or it could put the person at risk for serious side-effects.
Traditional Medicine
One-Size-Fits-All Approach - Some Benefit, Some Do Not
Personalized Medicine
Each Patient Benefits From Individualized Treatment
